What is MSM and what is it good for?
Methylsulfonylmethane, or MSM, is a natural sulfur compound that has become increasingly popular in health and wellness. Discover how MSM can support your body and why it's a sought-after ingredient in supplements and skincare.

Introduction
Methylsulfonylmethane (MSM) is an organic sulfur compound that occurs naturally in small amounts in foods such as fruits, vegetables, and dairy products.
The substance is also commonly found in supplements and skin care products. Interest in MSM has increased due to its potential therapeutic properties for joints, skin and hair.
This article presents scientific support for the health effects of MSM and its role in the body.
What is MSM?
MSM (methylsulfonylmethane) is an organic sulfur compound that is important for several biological processes, including the formation of connective tissue, collagen, and keratin.
Sulfur is a necessary constituent for protein structures essential for healthy skin, hair, nails, and articular cartilage (Butawan et al., 2017).
Health Benefits of MSM
1. Support for joints and mobility
Several studies indicate that MSM can reduce inflammation and relieve symptoms in osteoarthritis and joint pain.
A randomized controlled trial showed that daily intake of MSM reduced pain, stiffness, and improved physical function in people with knee osteoarthritis compared to placebo (Usha & Naidu, 2004). MSM is also thought to reduce oxidative stress and inflammation, which may be the mechanisms behind its positive effect on joints (Kim et al., 2006).
2. Promotes skin elasticity
MSM plays a central role in the synthesis of collagen, a protein that gives the skin its elasticity and strength.
Research indicates that MSM can improve skin texture and reduce signs of aging by stimulating collagen production and reducing inflammation (Muizzuddin et al., 2020).
3. Natural source of sulfur
Sulfur is an important mineral for the structure and functioning of the body. MSM is an easily absorbed source of sulfur that the body can effectively use to support important biological processes (Butawan et al., 2017).
4. Support for hair and nails
Because of MSM's role in the formation of keratin, the most important protein in hair and nails, supplementation of MSM can contribute to stronger and healthier hair and nails.
A pilot study showed that MSM supplementation resulted in noticeable improvement in hair growth and hair quality after 16 weeks of use (Muizzuddin et al., 2020).
How can you use MSM?
MSM comes in several different forms, making it easy to include in your daily routine. Here are some examples:
- Powder: MSM powder is easy to mix in water, juice or smoothies.
- Capsules or tablets: A convenient way to get MSM as a dietary supplement.
- Skin care products: MSM is often used in creams and serums to support the skin's natural functions.
Summary
Methylsulfonylmethane (MSM) is a scientifically supported, natural sulfur compound with the potential to improve joint health, skin elasticity, and strengthen hair and nails.
Several studies support its anti-inflammatory and antioxidant properties, making MSM a popular and effective supplement for those looking to optimize their health and well-being.
References:
- Butawan, M., Benjamin, R. L., & Bloomer, R. J. (2017). Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients, 9 (3), 290.
- Kim, Y. H., Kim, D. H., Lim, H., & Baek, D. Y. (2006). The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses. Journal of Experimental Biomedical Science, 12 (2), 95-101.
- Muizzuddin, N., Benjamin, R., & Beauty, F. (2020). Improvements in the appearance of facial wrinkles following topical application of methylsulfonylmethane (MSM). International Journal for Vitamin and Nutrition Research, 90 (1-2), 38-44.
- Usha, P. R., & Naidu, M. U. (2004). A randomised, double-blind, parallel, placebo-controlled study of oral glucosamine, methylsulfonylmethane and their combination in osteoarthritis. Clinical Drug Investigation, 24 (6), 353-363.



